Prediction: Atletico Madrid to win 2-1
Best Odds: 15/2
Bookmaker: Zetbet
Tottenham Hotspur and Atletico Madrid will lock horns with each other in the UEFA Champions League this week. The second leg of the last-16 tie between the Premier League club and the La Liga outfit will be held at Tottenham Hotspur Stadium and is scheduled to kick off at 8pm UK time on Wednesday evening. Atletico won the first leg 5-2 in Madrid last week.
Tottenham Hotspur
Tottenham Hotspur are one of the biggest clubs in the Premier League and always aim to finish in the top four. Spurs reached the final of the Champions League in 2019 and have strived to play in Europe’s premier club competition since.
Spurs won the UEFA Europa League last season, which allowed them to feature in the UEFA Champions League in the 2025-26 campaign. Although Tottenham have done well to progress to the last-16 stage, it seems that the north London club’s luck has run out.
Tottenham lost the first leg of the tie 5-2 to Atletico in Madrid last week. It is going to take a monumental effort from Igor Tudor’s side to overhaul the three-goal deficit. Spurs, though, played out an encouraging 1-1 draw with Liverpool away from home at Anfield in the Premier League last weekend to enhance their chances of escaping the dreaded drop to the Championship.
Team News:
Tottenham Hotspur are likely to line up in a 4-4-2 formation against Atletico Madrid this week. Guglielmo Vicario will be in goal and will have Pedro Porro, Kevin Danso, Radu Dragusin and Djed Spence in front of him in defence. Souza, Archie Gray, Pape Matar Sarr and Mathys Tel will be the four midfielders. Richarlison and Dominic Solanke will be the two centre-forwards.
Atletico Madrid
Atletico Madrid are one of the biggest clubs in Spain and regularly challenge for the La Liga title and compete in the UEFA Champions League. While Diego Simeone’s side are unlikely to become the champions of Spain this season, they are very much in contention for the UEFA Champions League.
Los Rojiblancos are third in the La Liga table at the moment with 57 points from 28 matches. Atletico are only two points above fourth-placed Villarreal and are 13 points behind leaders and defending champions Barcelona. However, the Madrid club are a foot in the quarter-finals of the UEFA Champions League, thanks to their 5-2 victory over Tottenham Hotspur in the first leg of the last-16 tie last week.
Atletico will head into the UEFA Champions League game against Tottenham this week on the back of a 1-0 victory over Getafe at home in La Liga. It came after a 5-2 hammering of Spurs in front of their fans in the UEFA Champions League, which followed a 3-2 win against Real Sociedad in the league.
Team News:
Atletico Madrid are likely to line up in a 3-5-2 formation against Tottenham Hotspur. Juan Musso will be in goal and will have Marc Pubill, Jose Maria Gimenez and Clement Lenglet in front of him in defence. Nahuel Molina, Obed Vargas, Koke, Thiago Almada and Nicolas Gonzalez will be the five midfielders. Alexander Sorloth and Alex Baena will be the two centre-forwards for Atletico.
Key Factors to Consider
- Tottenham Hotspur scored 17 goals and conceded 7 goals in 8 UEFA Champions League matches in the League Phase.
- Tottenham Hotspur took 11 shots against Atletico Madrid in the first leg, of which 5 were on target.
- Tottenham Hotspur had only 17 touches of the ball inside the Atletico Madrid penalty box.
- Atletico Madrid scored 17 goals and gave 15 goals in 8 UEFA Champions League matches in the League Phase.
- Atletico Madrid had 58% of the possession against Tottenham Hotspur in the first leg.
Conclusion
Atletico Madrid have a better team than Tottenham Hotspur and should be able to get the job done against Atletico Madrid this week.
Prediction: Atletico Madrid to win 2-1
Best Odds: 15/2
Bookmaker: Zetbet






